Microarray Technology And Its Applications PdfBy Millie R. In and pdf 20.03.2021 at 09:45 6 min read
File Name: microarray technology and its applications .zip
Microarray is one of the most recent advances being used for cancer research; it provides assistance in pharmacological approach to treat various diseases including oral lesions.
- Microarray and its applications
- The Role of Microarray Technology in Pharmaceutical Development and Diagnostics
- Application of microarray technology in pulmonary diseases
David W. Galbraith galbraith arizona. Jeremy Edwards edwardsjd ufl.
Scientists use DNA microarrays to measure the expression levels of large numbers of genes simultaneously or to genotype multiple regions of a genome. Probe-target hybridization is usually detected and quantified by detection of fluorophore -, silver-, or chemiluminescence -labeled targets to determine relative abundance of nucleic acid sequences in the target. Also for identification of structural variations and measurement of gene expression. The core principle behind microarrays is hybridization between two DNA strands, the property of complementary nucleic acid sequences to specifically pair with each other by forming hydrogen bonds between complementary nucleotide base pairs.
Microarray and its applications
Metrics details. Microarrays are a powerful tool that have multiple applications both in clinical and cell biology arenas of common lung diseases. To exemplify how this tool can be useful, in this review, we will provide an overview of the application of microarray technology in research relevant to common lung diseases and present some of the future perspectives. Microarray technology is rapidly becoming a standard technology used in research laboratories all across the world. Since its first application in the mid s [ 1 ] microarray technology has been successfully applied to almost every aspect of biomedical research [ 2 — 7 ] with over papers in respiratory research alone. Research conducted the last ten years has elevated the status of microarray technology from poorly understood and doubtfully applied in the fields of medicine to one that requires attention when the examination of clusters of genes in a single experiment is considered.
The Role of Microarray Technology in Pharmaceutical Development and Diagnostics
It seems that you're in Germany. We have a dedicated site for Germany. The genomics revolution would not have been possible without the 'parallelisation' offered by microarray technology. This technological - and commercial - success has been since emulated by other applications areas, with a tremendous amplification of innovation. This book describes the fundamentals and latest developments in microarray technology, as well as its future directions.
The DNA microarray is a tool used to determine whether the DNA from a particular individual contains a mutation in genes. Scientists know that a mutation - or alteration - in a particular gene's DNA may contribute to a certain disease. However, it can be very difficult to develop a test to detect these mutations, because most large genes have many regions where mutations can occur. For example, researchers believe that mutations in the genes BRCA1 and BRCA2 cause as many as 60 percent of all cases of hereditary breast and ovarian cancers. But there is not one specific mutation responsible for all of these cases. Researchers have already discovered over different mutations in BRCA1 alone. The chip consists of a small glass plate encased in plastic.
Microarray technology, with its high-throughput advantage, has been applied to analyze various biomaterials, such as nucleic acids, proteins.
Application of microarray technology in pulmonary diseases
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